ncRNA name | PTN siRNA |
ncRNA Category | siRNA |
Disease name | proliferative vitreoretinopathy (PVR) |
Species | Rattus norvegicus |
Tissues/Cell_line | retinas |
Methods | intravitreal injection, fundus images |
Expression pattern | associated |
Functional description | PTN silencing inhibited the up-regulation of claudin-1 and occludin stimulated by TGF-β1, and PTN knockdown inhibited the proliferative aspects of severe PVR in vivo. |
PubMed ID | 28083679 |
Year | 2017 |
Title | The effects of pleiotrophin in proliferative vitreoretinopathy. |
Drug-related ncRNA | NO |
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